Burton M Altura Selected Research

Magnesium Deficiency (Deficiency, Magnesium)

1/2014	Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.
1/2013	Magnesium deficiency upregulates sphingomyelinases in cardiovascular tissues and cells: cross-talk among proto-oncogenes, Mg(2+), NF-κB and ceramide and their potential relationships to resistant hypertension, atherogenesis and cardiac failure.
1/2012	Short-term magnesium deficiency upregulates ceramide synthase in cardiovascular tissues and cells: cross-talk among cytokines, Mg2+, NF-κB, and de novo ceramide.
12/2010	Short-term magnesium deficiency upregulates sphingomyelin synthase and p53 in cardiovascular tissues and cells: relevance to the de novo synthesis of ceramide.
9/2010	Magnesium deficiency upregulates serine palmitoyl transferase (SPT 1 and SPT 2) in cardiovascular tissues: relationship to serum ionized Mg and cytochrome c.
7/2009	Short-term magnesium deficiency results in decreased levels of serum sphingomyelin, lipid peroxidation, and apoptosis in cardiovascular tissues.
4/2002	Serum ionized magnesium levels and serum ionized calcium/ionized magnesium ratios in women with menstrual migraine.

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Burton M Altura Research Topics

Disease

10	Stroke (Strokes) 12/2003 - 06/2002
7	Magnesium Deficiency (Deficiency, Magnesium) 01/2014 - 04/2002
6	Hemorrhage 01/2012 - 07/2002
5	Atherosclerosis 01/2014 - 09/2003
5	Hypertension (High Blood Pressure) 01/2014 - 08/2002
4	Brain Injuries (Brain Injury) 01/2003 - 06/2002
3	Wounds and Injuries (Trauma) 01/2012 - 09/2009
3	Rupture 12/2002 - 07/2002
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2014 - 10/2004
2	Heart Failure 01/2014 - 01/2013
2	Infections 01/2012 - 09/2009
2	Shock 01/2012 - 01/2011
2	Sepsis (Septicemia) 01/2012 - 01/2011
2	Sickle Cell Anemia (Hemoglobin S Disease) 11/2004 - 05/2002
2	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2003 - 05/2003
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2003 - 10/2003
1	Ischemia 01/2011
1	Neoplasms (Cancer) 01/2011
1	Traumatic Shock 01/2011
1	Burns 09/2009
1	Bacterial Infections (Bacterial Infection) 09/2009
1	Necrosis 04/2007
1	Dehydration (Water Stress) 11/2004
1	Osteoporosis 10/2004
1	Alzheimer Disease (Alzheimer's Disease) 10/2004
1	Hypotension (Low Blood Pressure) 08/2004
1	Aortic Dissection 08/2004
1	Vascular Diseases (Vascular Disease) 03/2004
1	Vascular System Injuries 01/2003
1	Reperfusion Injury 07/2002
1	Spasm (Spasms) 07/2002
1	Headache (Headaches) 04/2002
1	Migraine Disorders (Migraine) 04/2002

Drug/Important Bio-Agent (IBA)

6	CeramidesIBA 01/2014 - 07/2002
6	NF-kappa B (NF-kB)IBA 01/2014 - 06/2002
6	MagnesiumIBA 04/2007 - 04/2002
4	CytokinesIBA 01/2014 - 09/2009
4	CalciumIBA 04/2007 - 04/2002
4	Ethanol (Ethyl Alcohol)IBA 12/2002 - 06/2002
3	EndotoxinsIBA 01/2012 - 09/2009
3	Biological ProductsIBA 01/2012 - 09/2009
3	Proteins (Proteins, Gene)FDA Link 01/2012 - 09/2009
3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2003 - 07/2002
2	Transcription Factors (Transcription Factor)IBA 01/2014 - 06/2002
2	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2014 - 07/2002
2	SphingomyelinsIBA 01/2013 - 07/2009
2	IsoenzymesIBA 01/2011 - 07/2002
2	Immunologic Factors (Immunomodulators)IBA 01/2011 - 09/2009
2	IonsIBA 04/2007 - 05/2003
2	Cocaine (Cocaine HCl)IBA 08/2004 - 12/2003
2	Peroxynitrous Acid (Peroxynitrite)IBA 03/2004 - 10/2003
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2014
1	EnzymesIBA 01/2013
1	Pharmaceutical PreparationsIBA 01/2013
1	dihydroceramide desaturaseIBA 01/2012
1	LipidsIBA 01/2011
1	Glutathione (Reduced Glutathione)IBA 01/2011
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2011
1	phosphatidylcholine-ceramide phosphocholine transferaseIBA 12/2010
1	Cytochromes c (Cytochrome c)IBA 09/2010
1	Serine (L-Serine)FDA Link 09/2010
1	TransferasesIBA 09/2010
1	Human Serum Albumin FDA LinkGeneric 09/2009
1	Peptides (Polypeptides)IBA 09/2009
1	Fibronectins (Fibronectin)IBA 09/2009
1	Complement System Proteins (Complement)IBA 09/2009
1	DefensinsIBA 09/2009
1	Choline (Choline Chloride)IBA 09/2009
1	TrioleinIBA 09/2009
1	Estrogens (Estrogen)FDA Link 10/2004
1	Free RadicalsIBA 03/2004
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 12/2003
1	prolinedithiocarbamate (PDTC)IBA 01/2003
1	pyrrolidine dithiocarbamic acidIBA 01/2003
1	CatalaseIBA 01/2003
1	AntioxidantsIBA 01/2003
1	Vitamin E FDA LinkGeneric 01/2003
1	Tosylphenylalanyl Chloromethyl Ketone (TPCK)IBA 12/2002
1	Phenylalanine (L-Phenylalanine)FDA Link 12/2002
1	KetonesIBA 12/2002
1	Mitogen-Activated Protein KinasesIBA 08/2002
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 08/2002
1	Peroxidase (Myeloperoxidase)IBA 07/2002
1	Phosphorylcholine (Phosphocholine)IBA 07/2002
1	Serotonin (5 Hydroxytryptamine)IBA 07/2002
1	Prostaglandins FIBA 07/2002
1	Phosphotransferases (Kinase)IBA 07/2002
1	Angiotensin IIIBA 07/2002
1	N-caproylsphingosineIBA 07/2002
1	N-palmitoylsphingosineIBA 07/2002
1	Glucosylceramides (Glucocerebrosides)IBA 07/2002
1	Hydroxyurea (Hydrea)FDA LinkGeneric 05/2002

Therapy/Procedure

2	Operative Surgical Procedures 01/2011 - 09/2009
2	Therapeutics 10/2004 - 05/2002
1	Surgical Amputation (Amputations) 01/2012
1	Hormone Replacement Therapy (Therapy, Hormone Replacement) 10/2004